Phase I Clinical Trial in healthy subjects shows that NM3086 was safe and well tolerated at all doses (0.1 to 20 mg/kg) in six cohorts. Total AP inhibition was achieved through all cohorts and the ...

Membranous nephropathy (MN) is an antibody-mediated autoimmune disease and a major cause of nephrotic syndrome in adult patients 1. Morphologically, granular deposition of immunoglobulins (IgG) and ...